Significance of circadian variations of uric acid elimination
Enteral uricolysis is increased at night whether fasting or not, yet the normal daily variation of urine urate excretion is lost during fasting. This indicates that circadian elimination via the gut is independent of renal function and food intake. As uricolysis is increased at night it is suggested...
Gespeichert in:
| Veröffentlicht in: | Annals of the rheumatic diseases 1983, Vol.42 (Suppl 1), p.87-87 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | Enteral uricolysis is increased at night whether fasting or not, yet the normal daily variation of urine urate excretion is lost during fasting. This indicates that circadian elimination via the gut is independent of renal function and food intake. As uricolysis is increased at night it is suggested that complex metabolic changes occur as a result of sleep that causes nucleoproteolysis and increased urate production with secondary renal effects of increased tubular reabsorption and reduced secretion of urate. |
|---|---|
| ISSN: | 0003-4967 1468-2060 |
| DOI: | 10.1136/ard.42.Suppl_1.87-a |