Prevotella oris -caused meningitis and spinal canal infection: A case report

-induced meningitis and -induced meningitis concomitant with spinal canal infection are extremely rare. To the best of our knowledge, only 1 case of -induced central system infection has been reported. This is the second report on meningitis combined with spinal canal infection due to . We report a case of a 9-year-old boy suffering from meningitis and spinal canal infection. The patient presented to the neurosurgery department with lumbosacral pain for 1 mo and headache and vomiting for 1 d. He had been treated with cephalosporin and nonsteroidal anti-inflammatory drugs for fever, otalgia and pharyngalgia in a local hospital 2 mo prior to this admission. During hospitalization, magnetic resonance imaging suggested meningitis and L3-S1 lumbosacral dural sac infection. The cerebrospinal fluid and blood cultures were negative, but the cerebrospinal fluid specimen indicated the presence of by metagenomic next-generation sequencing. Previous cases of infection were retrieved from PubMed to characterize the clinicopathological features and identify the prognostic factors and related antimicrobial treatment of infection due to . This report shed light on the characteristics of infection and highlighted the role of metagenomic next-generation sequencing in pathogen detection.