Toxic "ictal" confusion in middle age: treatment with benzodiazepines

In adult and elderly non-epileptic subjects psychoactive drugs may cause an altered state of consciousness and repetitive irritative EEG discharges. The neurotoxic pathogenesis of this drug-induced confusion and the differentiation from absence status are discussed. Dramatic relief by intravenous be...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1985-05, Vol.48 (5), p.472-476
1. Verfasser:	Van Sweden, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Benzodiazepinones - therapeutic use Biological and medical sciences Chlorpromazine - adverse effects Cimetidine - adverse effects Clonazepam - therapeutic use Cognition Disorders - drug therapy Confusion - chemically induced Confusion - diagnosis Confusion - drug therapy Dibenzazepines - adverse effects Electroencephalography Humans Medical sciences Methotrimeprazine - adverse effects Middle Aged Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology
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Beschreibung
Zusammenfassung:	In adult and elderly non-epileptic subjects psychoactive drugs may cause an altered state of consciousness and repetitive irritative EEG discharges. The neurotoxic pathogenesis of this drug-induced confusion and the differentiation from absence status are discussed. Dramatic relief by intravenous benzodiazepines is detailed. Recovery is complete and prognosis is excellent on withdrawal of the offending drug.
ISSN:	0022-3050 1468-330X
DOI:	10.1136/jnnp.48.5.472