The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory- Shigella spp

bacteria cause shigellosis, a gastrointestinal infection most often acquired from contaminated food or water. In this review, the general characteristics of bacteria are described, cases of laboratory-acquired infections (LAIs) are discussed, and evidence gaps in current biosafety practices are identified. LAIs are undoubtedly under-reported. Owing to the low infectious dose, rigorous biosafety level 2 practices are required to prevent LAIs resulting from sample manipulation or contact with infected surfaces. It is recommended that, before laboratory work with , an evidence-based risk assessment be conducted. Particular emphasis should be placed on personal protective equipment, handwashing, and containment practices for procedures that generate aerosols or droplets.