Evaluation of a Fourth-Generation Subcutaneous Real-Time Continuous Glucose Monitor (CGM) in Individuals With Diabetes on Peritoneal Dialysis
To evaluate the performance of a real-time continuous glucose monitor (CGM) in individuals with diabetes on peritoneal dialysis (PD). Thirty participants with type 2 diabetes on continuous ambulatory PD wore a Guardian Sensor 3 on the upper arm paired with Guardian Connect for 14 days. We compared C...
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| Veröffentlicht in: | Diabetes care 2023-06, Vol.46 (6), p.1191-1195 |
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| container_title | Diabetes care |
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| creator | Ng, Jack K C Ling, James Luk, Andrea O Y Lau, Eric S H Ma, Ronald C W Li, Philip K T Szeto, Cheuk Chun Chan, Juliana C N Chow, Elaine |
| description | To evaluate the performance of a real-time continuous glucose monitor (CGM) in individuals with diabetes on peritoneal dialysis (PD).
Thirty participants with type 2 diabetes on continuous ambulatory PD wore a Guardian Sensor 3 on the upper arm paired with Guardian Connect for 14 days. We compared CGM readings against Yellow Springs Instrument (YSI) venous glucose during an 8-h in-clinic session with glucose challenge.
The mean absolute relative difference (MARD) was 10.4% (95% CI 9.6, 11.7) from 941 CGM-YSI matched pairs; 81.3% of readings were within %15/15 of YSI values in the full glycemic range. Consensus error grid analysis showed 99.9% of sensor values in zones A and B. There were no correlations between pH, uremia, hydration status, and MARD.
We showed satisfactory performance of a real-time CGM sensor in PD patients with diabetes, supporting future use to facilitate treatment decisions. |
| doi_str_mv | 10.2337/dc22-2348 |
| format | Article |
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Thirty participants with type 2 diabetes on continuous ambulatory PD wore a Guardian Sensor 3 on the upper arm paired with Guardian Connect for 14 days. We compared CGM readings against Yellow Springs Instrument (YSI) venous glucose during an 8-h in-clinic session with glucose challenge.
The mean absolute relative difference (MARD) was 10.4% (95% CI 9.6, 11.7) from 941 CGM-YSI matched pairs; 81.3% of readings were within %15/15 of YSI values in the full glycemic range. Consensus error grid analysis showed 99.9% of sensor values in zones A and B. There were no correlations between pH, uremia, hydration status, and MARD.
We showed satisfactory performance of a real-time CGM sensor in PD patients with diabetes, supporting future use to facilitate treatment decisions.</description><identifier>ISSN: 0149-5992</identifier><identifier>EISSN: 1935-5548</identifier><identifier>DOI: 10.2337/dc22-2348</identifier><identifier>PMID: 37043824</identifier><language>eng</language><publisher>United States: American Diabetes Association</publisher><subject>Blood Glucose ; Blood Glucose Self-Monitoring ; Brief Report ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 1 ; Diabetes Mellitus, Type 2 ; Dialysis ; Error analysis ; Glucose ; Glucose monitoring ; Humans ; Performance evaluation ; Peritoneal Dialysis ; Peritoneum ; Real time ; Reproducibility of Results ; Research design ; Uremia</subject><ispartof>Diabetes care, 2023-06, Vol.46 (6), p.1191-1195</ispartof><rights>2023 by the American Diabetes Association.</rights><rights>Copyright American Diabetes Association Jun 2023</rights><rights>2023 by the American Diabetes Association 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-4ea9255ec014d96493ebd9b3a29d5808708c31100a6a6d17b9a0344e0a79707b3</citedby><cites>FETCH-LOGICAL-c404t-4ea9255ec014d96493ebd9b3a29d5808708c31100a6a6d17b9a0344e0a79707b3</cites><orcidid>0000-0002-4147-3387</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37043824$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ng, Jack K C</creatorcontrib><creatorcontrib>Ling, James</creatorcontrib><creatorcontrib>Luk, Andrea O Y</creatorcontrib><creatorcontrib>Lau, Eric S H</creatorcontrib><creatorcontrib>Ma, Ronald C W</creatorcontrib><creatorcontrib>Li, Philip K T</creatorcontrib><creatorcontrib>Szeto, Cheuk Chun</creatorcontrib><creatorcontrib>Chan, Juliana C N</creatorcontrib><creatorcontrib>Chow, Elaine</creatorcontrib><title>Evaluation of a Fourth-Generation Subcutaneous Real-Time Continuous Glucose Monitor (CGM) in Individuals With Diabetes on Peritoneal Dialysis</title><title>Diabetes care</title><addtitle>Diabetes Care</addtitle><description>To evaluate the performance of a real-time continuous glucose monitor (CGM) in individuals with diabetes on peritoneal dialysis (PD).
Thirty participants with type 2 diabetes on continuous ambulatory PD wore a Guardian Sensor 3 on the upper arm paired with Guardian Connect for 14 days. We compared CGM readings against Yellow Springs Instrument (YSI) venous glucose during an 8-h in-clinic session with glucose challenge.
The mean absolute relative difference (MARD) was 10.4% (95% CI 9.6, 11.7) from 941 CGM-YSI matched pairs; 81.3% of readings were within %15/15 of YSI values in the full glycemic range. Consensus error grid analysis showed 99.9% of sensor values in zones A and B. There were no correlations between pH, uremia, hydration status, and MARD.
We showed satisfactory performance of a real-time CGM sensor in PD patients with diabetes, supporting future use to facilitate treatment decisions.</description><subject>Blood Glucose</subject><subject>Blood Glucose Self-Monitoring</subject><subject>Brief Report</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 1</subject><subject>Diabetes Mellitus, Type 2</subject><subject>Dialysis</subject><subject>Error analysis</subject><subject>Glucose</subject><subject>Glucose monitoring</subject><subject>Humans</subject><subject>Performance evaluation</subject><subject>Peritoneal Dialysis</subject><subject>Peritoneum</subject><subject>Real time</subject><subject>Reproducibility of Results</subject><subject>Research design</subject><subject>Uremia</subject><issn>0149-5992</issn><issn>1935-5548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV9rFDEUxYModq0--AUk4Ev7MJp_M0meRNZ2LbQobcXHkJm566bMJjV_Fvoh-p2bYWtRny6c--Nw7zkIvaXkA-NcfhwHxhrGhXqGFlTztmlboZ6jBaFCN63W7AC9SumGECKEUi_RAZdEcMXEAt2f7OxUbHbB47DGFp-GEvOmWYGHuJevSj-UbD2EkvAl2Km5dlvAy-Cz82UWV1MZQgJ8EbzLIeKj5eriGDuPz_zodm4sdkr4p8sb_MXZHjIkXH2_Q6y0r4azPN0ll16jF-vKwpvHeYh-nJ5cL782599WZ8vP580giMiNAKtZ28JQHxx1JzSHftQ9t0yPrSJKEjVwSgmxne1GKnttCRcCiJVaEtnzQ_Rp73tb-i2MA_gc7WRuo9vaeGeCdebfjXcb8yvsDCU1Zim66nD06BDD7wIpm61LA0zTPifDFCEd64jSFX3_H3pTM_b1v0pR3SlJpazU8Z4aYkgpwvrpGkrM3LKZWzZzy5V99_f5T-SfWvkDQWWjTA</recordid><startdate>20230601</startdate><enddate>20230601</enddate><creator>Ng, Jack K C</creator><creator>Ling, James</creator><creator>Luk, Andrea O Y</creator><creator>Lau, Eric S H</creator><creator>Ma, Ronald C W</creator><creator>Li, Philip K T</creator><creator>Szeto, Cheuk Chun</creator><creator>Chan, Juliana C N</creator><creator>Chow, Elaine</creator><general>American Diabetes Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4147-3387</orcidid></search><sort><creationdate>20230601</creationdate><title>Evaluation of a Fourth-Generation Subcutaneous Real-Time Continuous Glucose Monitor (CGM) in Individuals With Diabetes on Peritoneal Dialysis</title><author>Ng, Jack K C ; 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Thirty participants with type 2 diabetes on continuous ambulatory PD wore a Guardian Sensor 3 on the upper arm paired with Guardian Connect for 14 days. We compared CGM readings against Yellow Springs Instrument (YSI) venous glucose during an 8-h in-clinic session with glucose challenge.
The mean absolute relative difference (MARD) was 10.4% (95% CI 9.6, 11.7) from 941 CGM-YSI matched pairs; 81.3% of readings were within %15/15 of YSI values in the full glycemic range. Consensus error grid analysis showed 99.9% of sensor values in zones A and B. There were no correlations between pH, uremia, hydration status, and MARD.
We showed satisfactory performance of a real-time CGM sensor in PD patients with diabetes, supporting future use to facilitate treatment decisions.</abstract><cop>United States</cop><pub>American Diabetes Association</pub><pmid>37043824</pmid><doi>10.2337/dc22-2348</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-4147-3387</orcidid><oa>free_for_read</oa></addata></record> |
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| issn | 0149-5992 1935-5548 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Blood Glucose Blood Glucose Self-Monitoring Brief Report Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Dialysis Error analysis Glucose Glucose monitoring Humans Performance evaluation Peritoneal Dialysis Peritoneum Real time Reproducibility of Results Research design Uremia |
| title | Evaluation of a Fourth-Generation Subcutaneous Real-Time Continuous Glucose Monitor (CGM) in Individuals With Diabetes on Peritoneal Dialysis |
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