Sodium-glucose cotransporter 2 inhibitor-associated perioperative ketoacidosis: a systematic review of case reports

Sodium-glucose cotransporter 2 inhibitor-associated perioperative ketoacidosis: a systematic review of case reports

Although the recommended preoperative cessation period for sodium-glucose cotransporter 2 inhibitors (SGLT2is) changed in 2020 (from 24 h to 3–4 days preoperatively) to reduce the risk of SGLT2i-associated perioperative ketoacidosis (SAPKA), the validity of the new recommendation has not been verifi...

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Veröffentlicht in:Journal of anesthesia 2023-06, Vol.37 (3), p.465-473
Hauptverfasser: Seki, Hiroyuki, Ideno, Satoshi, Shiga, Toshiya, Watanabe, Hidenobu, Ono, Motoaki, Motoyasu, Akira, Noguchi, Hikari, Kondo, Kazuya, Yoshikawa, Takahiro, Hoshijima, Hiroshi, Hyuga, Shunsuke, Shishii, Miho, Nagai, Ai, Higashi, Midoriko, Ouchi, Takashi, Yasuda, Kazuki, Kuratani, Norifumi
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesiology
Critical Care Medicine
Dextrose
Diabetes Mellitus, Type 2 - chemically induced
Diabetes Mellitus, Type 2 - complications
Diabetic acidosis
Diabetic Ketoacidosis - chemically induced
Emergency Medicine
Glucose
Glycosylated hemoglobin
Humans
Hypoglycemic agents
Intensive
Ketoacidosis
Ketosis - chemically induced
Ketosis - complications
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Pain Medicine
Prospective Studies
Review
Review Article
Risk factors
Sodium
Sodium-Glucose Transporter 2 Inhibitors - adverse effects
Type 2 diabetes
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Zusammenfassung:Although the recommended preoperative cessation period for sodium-glucose cotransporter 2 inhibitors (SGLT2is) changed in 2020 (from 24 h to 3–4 days preoperatively) to reduce the risk of SGLT2i-associated perioperative ketoacidosis (SAPKA), the validity of the new recommendation has not been verified. Using case reports, we assessed the new recommendation effectiveness and extrapolated precipitating factors for SAPKA. We searched electronic databases up to June 1, 2022 to assess SAPKA (blood pH 
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-023-03174-8