Autosomal dominant polycystic kidney disease in young adults

Autosomal dominant polycystic kidney disease in young adults

Background The clinical manifestations of autosomal dominant polycystic kidney disease (ADPKD) usually appear in adulthood, however pediatric series report a high morbidity. The objective of the study was to analyze the clinical characteristics of ADPKD in young adults. Methods Family history, hyper...

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Veröffentlicht in:Clinical kidney journal 2023-06, Vol.16 (6), p.985-995
Hauptverfasser: Martínez, Víctor, Furlano, Mónica, Sans, Laia, Pulido, Lissett, García, Rebeca, Pérez-Gómez, María Vanessa, Sánchez-Rodríguez, Jinny, Blasco, Miquel, Castro-Alonso, Cristina, Fernández-Fresnedo, Gema, Robles, Nicolás Roberto, Valenzuela, María Pau, Naranjo, Javier, Martín, Nadia, Pilco, Melissa, Agraz-Pamplona, Irene, González-Rodríguez, Juan David, Panizo, Nayara, Fraga, Gloria, Fernández, Loreto, López, María Teresa, Dall'Anese, Cecilia, Ortiz, Alberto, Torra, Roser
Format: Artikel
Sprache:eng
Schlagworte:
Aneurysms
Blood pressure
Hypertension
Liver
Measurement
Original
Pediatrics
Polycystic kidney disease
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Zusammenfassung:Background The clinical manifestations of autosomal dominant polycystic kidney disease (ADPKD) usually appear in adulthood, however pediatric series report a high morbidity. The objective of the study was to analyze the clinical characteristics of ADPKD in young adults. Methods Family history, hypertension, albuminuria, estimated glomerular filtration rate (eGFR) and imaging tests were examined in 346 young adults (18–30 years old) out of 2521 patients in the Spanish ADPKD registry (REPQRAD). A literature review searched for reports on hypertension in series with more than 50 young (age
ISSN:2048-8505
2048-8513
DOI:10.1093/ckj/sfac251