Early timing of ablation after diagnosis: a powerful way to reduce atrial fibrillation recurrence

Abstract Funding Acknowledgements Type of funding sources: None. Background Diagnosis-to-ablation time (DAT) is a strong, modifiable predictor of AF recurrence after ablation. Referral time for ablation, and hence DAT became shorter over time. Purpose To search for the shortest DAT still impacting outcome and to look at the evolution of the "DAT-AF recurrence" relation over time in a wide range of DAT. Methods and results Two cohorts of 1000 AF patients (69% males, age 62±10 years) undergoing PVI (2006-2014 and 2017-2019) were followed for 3years. Clinical success, defined as freedom of documented AF was achieved in 61,7% of patients. Independent predictors of clinical success were age (HR=1,01; 95%CI 1,01-1,02; p 0,003), AF type (HR=0.54; 95%CI 0.46-0.63; p