Invasion of undifferentiated pleomorphic sarcoma (UPS) in breast tissue; a case report study

Breast sarcomas are scarce, histologically heterogeneous with nonepithelial malignancies that originate from the connective tissue within the parenchyma of breast. They can develop primarily, after radio-therapy (RT), or secondary due to chronic condition, including metastatic cancers. The present case report concerns 58-year-old women which was unbeknown to her malignancy in the early stages, until the mass became substantial in size. Chemotherapy and also radiotherapy were not effective, and the growth of tumor could not be prevented which the patient eventually died, due to respiratory complications. Breast sarcomas are categorized in very rare malignancies, and the mortality of these types of cancers are significantly high as they often are not diagnosed in early stages. Based on the location and condition of the malignant tumor, therapeutic methods considered as chemotherapy, radiotherapy, and surgery. In advance stages of breast sarcoma, chemotherapy, radiotherapy, and even surgery cannot be effectual. Therefore, periodical evaluation of breast wellness by diagnostic methods are recommended to all adult women. •Breast sarcoma is a rare form of malignancy.•Undifferentiated pleomorphic sarcoma (UPS) constitutes less than of all sarcomas in adults.•Wide surgical excision with clear surgical margins is the most effective treatment.