Dietary Patterns, Apolipoprotein L1 Risk Genotypes, and CKD Outcomes Among Black Adults in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort Study

Dietary factors may impact inflammation and interferon production, which could influence phenotypic expression of Apolipoprotein1 (APOL1) genotypes. We investigated whether associations of dietary patterns with kidney outcomes differed by APOL1 genotypes. Prospective cohort. 5,640 Black participants...

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Veröffentlicht in:	Kidney medicine 2023-05, Vol.5 (5), p.100621-100621, Article 100621
Hauptverfasser:	Ilori, Titilayo O., Brooks, Marquita S., Desai, Parin N., Cheung, Katharine L., Judd, Suzanne E., Crews, Deidra C., Cushman, Mary, Winkler, Cheryl A., Shlipak, Michael G., Kopp, Jeffrey B., Naik, Rakhi P., Estrella, Michelle M., Gutiérrez, Orlando M., Kramer, Holly
Format:	Artikel
Sprache:	eng
Schlagworte:	APOL1 genotypes Apolipoprotein L1 chronic kidney disease dietary patterns ESKD inflammation kidney failure Original Research Plant pattern Southern pattern
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Zusammenfassung:	Dietary factors may impact inflammation and interferon production, which could influence phenotypic expression of Apolipoprotein1 (APOL1) genotypes. We investigated whether associations of dietary patterns with kidney outcomes differed by APOL1 genotypes. Prospective cohort. 5,640 Black participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS). Five dietary patterns derived from food frequency questionnaires: Convenience foods, Southern, Sweets and Fats, Plant-based, and Alcohol/Salads. Incident chronic kidney disease (CKD), CKD progression, and kidney failure. Incident CKD was defined as a change in estimated glomerular filtration rate (eGFR) to
ISSN:	2590-0595 2590-0595
DOI:	10.1016/j.xkme.2023.100621