Determinants of medication adherence in childhood nephrotic syndrome and associations of adherence with clinical outcomes

Background Pediatric patients with nephrotic syndrome take medications long-term with significant toxicity and complex regimens, yet data on medication adherence are limited. Methods In a multicenter observational study of patients with nephrotic syndrome, NEPTUNE (NCT01209000), we surveyed caregive...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2022-07, Vol.37 (7), p.1585-1595
Hauptverfasser:	Wang, Chia-shi, Troost, Jonathan P, Wang, Yujie, Greenbaum, Larry A, Gibson, Keisha, Trachtman, Howard, Srivastava, Tarak, Reidy, Kimberly, Kaskel, Frederick, Sethna, Christine B, Meyers, Kevin, Dell, Katherine M, Tran, Cheryl L, Hingorani, Sangeeta, Lemley, Kevin V, Lin, Jen-Jar, Gipson, Debbie S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Childhood Children Classification Clinical outcomes Drug therapy Health care Health services utilization Humans Kidney diseases Management Medication Adherence Medicine Medicine & Public Health Nephrology Nephrotic syndrome Nephrotic Syndrome - drug therapy Original Article Patient compliance Patient outcomes Patients Pediatric research Pediatrics Statistical analysis Steroids Surveys and Questionnaires Teenagers Toxicity Urology Young Adult
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Beschreibung
Zusammenfassung:	Background Pediatric patients with nephrotic syndrome take medications long-term with significant toxicity and complex regimens, yet data on medication adherence are limited. Methods In a multicenter observational study of patients with nephrotic syndrome, NEPTUNE (NCT01209000), we surveyed caregivers of patients
ISSN:	0931-041X 1432-198X 1432-198X
DOI:	10.1007/s00467-021-05176-8