LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase

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Bibliographische Detailangaben
Veröffentlicht in:	Circulation research 2020-09, Vol.127 (8), p.1112-1114
Hauptverfasser:	Wu, Liya, Soundarapandian, Mangala M., Castoreno, Adam B., Millar, John S., Rader, Daniel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiopoietin-Like Protein 3 Angiopoietin-like Proteins - genetics Angiopoietin-like Proteins - metabolism Animals Biomarkers - blood Cholesterol, LDL - blood Disease Models, Animal Down-Regulation Hypercholesterolemia - blood Hypercholesterolemia - genetics Hypercholesterolemia - therapy Lipase - genetics Lipase - metabolism Liver - metabolism Mice, Knockout Receptors, LDL - genetics Receptors, LDL - metabolism RNA Interference RNA, Small Interfering - genetics RNA, Small Interfering - metabolism RNAi Therapeutics
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