Prediabetes, diabetes and loss of disability-free survival in a community-based older cohort: a post-hoc analysis of the ASPirin in Reducing Events in the Elderly trial
Abstract Background Evidence for the prognostic implications of hyperglycaemia in older adults is inconsistent. Objective To evaluate disability-free survival (DFS) in older individuals by glycaemic status. Methods This analysis used data from a randomised trial recruiting 19,114 community-based par...
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Veröffentlicht in: | Age and ageing 2023-04, Vol.52 (4) |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Abstract
Background
Evidence for the prognostic implications of hyperglycaemia in older adults is inconsistent.
Objective
To evaluate disability-free survival (DFS) in older individuals by glycaemic status.
Methods
This analysis used data from a randomised trial recruiting 19,114 community-based participants aged ≥70 years, who had no prior cardiovascular events, dementia and physical disability. Participants with sufficient information to ascertain their baseline diabetes status were categorised as having normoglycaemia (fasting plasma glucose [FPG] |
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ISSN: | 0002-0729 1468-2834 |
DOI: | 10.1093/ageing/afad060 |