Sequencing of Circulating Cell-free DNA during Pregnancy

Advances in DNA sequencing have facilitated a change in the method used to screen for fetal chromosome trisomies. This review describes the basis and development of the method.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2018-08, Vol.379 (5), p.464-473
Hauptverfasser:	Bianchi, Diana W, Chiu, Rossa W.K
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell-Free Nucleic Acids - analysis Chromosome Aberrations False Negative Reactions False Positive Reactions Female Fetus Humans Male Mutation Pregnancy Prenatal Diagnosis - methods Sequence Analysis, DNA - ethics Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Advances in DNA sequencing have facilitated a change in the method used to screen for fetal chromosome trisomies. This review describes the basis and development of the method.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMra1705345