Discussion of Research Priorities for Gait Disorders in Parkinson's Disease

ABSTRACT Gait and balance abnormalities develop commonly in Parkinson's disease and are among the motor symptoms most disabling and refractory to dopaminergic or other treatments, including deep brain stimulation. Efforts to develop effective therapies are challenged by limited understanding of...

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Veröffentlicht in:Movement disorders 2022-02, Vol.37 (2), p.253-263
Hauptverfasser: Bohnen, Nicolaas I., Costa, Rui M., Dauer, William T., Factor, Stewart A., Giladi, Nir, Hallett, Mark, Lewis, Simon J.G., Nieuwboer, Alice, Nutt, John G., Takakusaki, Kaoru, Kang, Un Jung, Przedborski, Serge, Papa, Stella M.
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Sprache:eng
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Zusammenfassung:ABSTRACT Gait and balance abnormalities develop commonly in Parkinson's disease and are among the motor symptoms most disabling and refractory to dopaminergic or other treatments, including deep brain stimulation. Efforts to develop effective therapies are challenged by limited understanding of these complex disorders. There is a major need for novel and appropriately targeted research to expedite progress in this area. The Scientific Issues Committee of the International Parkinson and Movement Disorder Society has charged a panel of experts in the field to consider the current knowledge gaps and determine the research routes with highest potential to generate groundbreaking data. © 2021 International Parkinson and Movement Disorder Society
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.28883