A guide to naming eukaryotic circular RNAs

Alternative splicing of eukaryotic messenger RNA transcripts often leads to the production of several mature RNAs — including linear RNAs and circular RNAs (circRNAs) — from a single gene locus. The names given to circRNAs are often ambiguous and lack consistency across studies. This Comment calls o...

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Veröffentlicht in:	Nature cell biology 2023-01, Vol.25 (1), p.1-5
Hauptverfasser:	Chen, Ling-Ling, Bindereif, Albrecht, Bozzoni, Irene, Chang, Howard Y., Matera, A. Gregory, Gorospe, Myriam, Hansen, Thomas B., Kjems, Jørgen, Ma, Xu-Kai, Pek, Jun Wei, Rajewsky, Nikolaus, Salzman, Julia, Wilusz, Jeremy E., Yang, Li, Zhao, Fangqing
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/337/384 Alternative splicing Biology Biomedical and Life Sciences Cancer Research Cell Biology Comment Developmental Biology Eukaryota - genetics Eukaryotic Cells Life Sciences MicroRNAs mRNA Names Naming Nomenclature Reproducibility RNA - genetics RNA, Circular Splicing Stem Cells
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Zusammenfassung:	Alternative splicing of eukaryotic messenger RNA transcripts often leads to the production of several mature RNAs — including linear RNAs and circular RNAs (circRNAs) — from a single gene locus. The names given to circRNAs are often ambiguous and lack consistency across studies. This Comment calls on the community to embrace a common nomenclature for naming circRNAs to ensure clarity and reproducibility.
ISSN:	1465-7392 1476-4679
DOI:	10.1038/s41556-022-01066-9