Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review

Necrotizing Soft Tissue Infections in South Australia: A 15-Year Review

Abstract Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidenc...

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Veröffentlicht in:Open Forum Infectious Diseases 2023-04, Vol.10 (4), p.ofad117-ofad117
Hauptverfasser: Tam, Patrick Chung Kay, Kennedy, Brendan, Ashokan, Anushia
Format: Artikel
Sprache:eng
Schlagworte:
Australia
Brief Report
Epidemiology
Infection
Medical colleges
Methicillin
Mortality
Tazobactam
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Zusammenfassung:Abstract Necrotizing soft tissue infections (NSTIs) are associated with high morbidity and mortality. We retrospectively examined the impact of empiric antimicrobials coupled with early surgery on mortality in NSTI. Early surgery independently reduced 30-day mortality (odds ratio, .16; 95% confidence interval, .05–.51; P < .001) that was not further augmented by empiric antimicrobial choice.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofad117