A nationwide prospective cohort study on safety of the 17D-204 yellow fever vaccine during a vaccine shortage in Japan

In response to the vaccine shortage of yellow fever vaccine (YF-VAX) due to manufacturing delays, the unapproved 17D-204 YF-VAX was used as an investigator-initiated clinical trial in Japan. The vaccine was administered to 11 279 participants in 19 YF vaccination centres in Japan, and few serious ad...

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Veröffentlicht in:	Journal of travel medicine 2023-04, Vol.30 (2)
Hauptverfasser:	Miyazato, Yusuke, Terada, Mari, Ujiie, Mugen, Saito, Sho, Moriya, Akinari, Ando, Masao, Ohmagari, Norio
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Viral Fever Humans Japan Prospective Studies Research Letter Shortages Vaccines Vector-borne diseases Yellow fever Yellow Fever - prevention & control Yellow Fever Vaccine Yellow fever virus
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Beschreibung
Zusammenfassung:	In response to the vaccine shortage of yellow fever vaccine (YF-VAX) due to manufacturing delays, the unapproved 17D-204 YF-VAX was used as an investigator-initiated clinical trial in Japan. The vaccine was administered to 11 279 participants in 19 YF vaccination centres in Japan, and few serious adverse events were observed.
ISSN:	1195-1982 1708-8305
DOI:	10.1093/jtm/taac070