Real-world use of defibrotide for veno-occlusive disease/sinusoidal obstruction syndrome: the DEFIFrance Registry Study

Real-world use of defibrotide for veno-occlusive disease/sinusoidal obstruction syndrome: the DEFIFrance Registry Study

Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of haematopoietic cell transplantation (HCT) conditioning. The DEFIFrance post-marketing registry study evaluated effectiveness and safety in patients who received defibrotide. It collecte...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bone marrow transplantation (Basingstoke) 2023-04, Vol.58 (4), p.367-376
Hauptverfasser: Mohty, Mohamad, Blaise, Didier, Peffault de Latour, Régis, Labopin, Myriam, Bourhis, Jean Henri, Bruno, Benedicte, Ceballos, Patrice, Detrait, Marie, Gandemer, Virginie, Huynh, Anne, Izadifar-Legrand, Faezeh, Jubert, Charlotte, Labussière-Wallet, Hélène, Lebon, Delphine, Maury, Sébastien, Paillard, Catherine, Pochon, Cécile, Renard, Cecile, Rialland, Fanny, Schneider, Pascale, Sirvent, Anne, Asubonteng, Kobby, Guindeuil, Gwennaëlle, Yakoub-Agha, Ibrahim, Dalle, Jean-Hugues
Format: Artikel
Sprache:eng
Schlagworte:
631/532/1542
692/700/565/1436
Bilirubin
Cell Biology
Chemotherapy
Disease prevention
Health services
Hematology
Hematopoietic Stem Cell Transplantation - adverse effects
Hematopoietic stem cells
Hepatic Veno-Occlusive Disease - drug therapy
Hepatic Veno-Occlusive Disease - etiology
Human health and pathology
Humans
Internal Medicine
Life Sciences
Medical prognosis
Medicine
Medicine & Public Health
Mortality
Patients
Pediatrics
Prophylaxis
Prospective Studies
Public Health
Registries
Retrospective Studies
Risk factors
Sine waves
Stem cell transplantation
Stem Cells
Survival
Transplantation
Transplants & implants
Veno-occlusive disease
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is a potentially life-threatening complication of haematopoietic cell transplantation (HCT) conditioning. The DEFIFrance post-marketing registry study evaluated effectiveness and safety in patients who received defibrotide. It collected retrospective/prospective patient data from 53 French HCT centres from July 2014 to March 2020. Primary endpoints were survival and complete response (CR; total serum bilirubin
ISSN:0268-3369
1476-5365
DOI:10.1038/s41409-022-01900-6