An embarrassment of riches: RORγt+ antigen-presenting cells in peripheral tolerance

RORγt+ regulatory T (Treg) cells are critical toward maintaining gut immune tolerance. In recent studies published in Nature, Kedmi et al., Lyu et al., and Akagbosu et al. describe MHCII+RORγt+ antigen-presenting cells that mediate RORγt+ Treg cell differentiation but propose disparate identities fo...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2022-11, Vol.55 (11), p.1978-1980
Hauptverfasser:	Stephen-Victor, Emmanuel, Chatila, Talal A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Presenting Cells Embarrassment Forkhead Transcription Factors Immune Tolerance Nuclear Receptor Subfamily 1, Group F, Member 3 Peripheral Tolerance T-Lymphocytes, Regulatory Th17 Cells
Online-Zugang:	Volltext
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