The representation of females in clinical trials for substance use disorder conducted in the United States (2010–19)

Background and aims Women have historically been under‐represented in clinical research, but the extent to which this is true for substance use disorder (SUD) trials is unknown. We aimed to determine the ratio of female:male participation in clinical trials for SUDs and describe the reporting of sex‐specific outcomes from 2010 to 2019. Design A retrospective cohort review of clinical trials involving people with SUD. Setting United States. Participants Clinical trials including people with SUD registered in clinicaltrials.gov and completed between 1 January 2010 and 31 December 2019 were reviewed. Trials were excluded if they had