On-Demand, Reversible, Ultrasensitive Polymer Membrane Based on Molecular Imprinting Polymer

On-Demand, Reversible, Ultrasensitive Polymer Membrane Based on Molecular Imprinting Polymer

The development of in vivo, longitudinal, real-time monitoring devices is an essential step toward continuous, precision health monitoring. Molecularly imprinted polymers (MIPs) are popular sensor capture agents that are more robust than antibodies and have been used for sensors, drug delivery, affi...

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Veröffentlicht in:ACS nano 2023-03, Vol.17 (6), p.5632-5643
Hauptverfasser: Mintz Hemed, Nofar, Leal-Ortiz, Sergio, Zhao, Eric T., Melosh, Nicholas A.
Format: Artikel
Sprache:eng
Schlagworte:
Biosensing Techniques
Dopamine
Electrochemical Techniques
Molecular Imprinting
Polymers - chemistry
Povidone
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Zusammenfassung:The development of in vivo, longitudinal, real-time monitoring devices is an essential step toward continuous, precision health monitoring. Molecularly imprinted polymers (MIPs) are popular sensor capture agents that are more robust than antibodies and have been used for sensors, drug delivery, affinity separations, assays, and solid-phase extraction. However, MIP sensors are typically limited to one-time use due to their high binding affinity (>107 M–1) and slow-release kinetics (
ISSN:1936-0851
1936-086X
DOI:10.1021/acsnano.2c11618