Characteristics Associated With 5-Year Fracture Risk Versus 5-Year Mortality Risk Among Late-Life Men

Abstract Background Identifying late-life men who might benefit from treatment to prevent fracture is challenging given high mortality. Our objective was to evaluate risks of clinical fracture, hip fracture, and mortality prior to fracture among men aged at least 80 years. Methods Study participants...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2023-03, Vol.78 (4), p.683-689
Hauptverfasser:	Langsetmo, Lisa, Schousboe, John T, Taylor, Brent C, Cauley, Jane A, Fink, Howard A, Cawthon, Peggy M, Stefanick, Marcia L, Kado, Deborah M, Kats, Allyson M, Ensrud, Kristine E
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Bone Density Bone mineral density COVID-19 Fracture toughness Fractures Hip Hip Fractures - epidemiology Hip Fractures - etiology Hip joint Humans Life span Male Mortality Osteoporosis Osteoporosis - complications Osteoporotic Fractures - epidemiology Risk assessment Risk Factors THE JOURNAL OF GERONTOLOGY: Medical Sciences
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Zusammenfassung:	Abstract Background Identifying late-life men who might benefit from treatment to prevent fracture is challenging given high mortality. Our objective was to evaluate risks of clinical fracture, hip fracture, and mortality prior to fracture among men aged at least 80 years. Methods Study participants included 3 145 community-dwelling men (mean [standard deviation] age 83 [2.8] years) from the Osteoporotic Fractures in Men (MrOS) Study. We used separate multivariable Fine-Gray competing risk models with prespecified risk factors (age, hip bone mineral density [BMD], recent fracture [
ISSN:	1079-5006 1758-535X 1758-535X
DOI:	10.1093/gerona/glac159