Calorie and Time Restriction in Weight Loss

Weight loss with calorie restriction is the recommended approach for treatment of obesity, but this approach is resource-intensive and difficult to sustain over time. 1 Time-restricted eating is a potentially low-cost and sustainable lifestyle in which daily intake of calories is restricted to a consistent time period of less than 10 hours without explicit attempts to modify diet composition or reduce calories. Chronic disruption of the circadian rhythm increases the risk of obesity and metabolic diseases. Restricting the window of time for eating sustains circadian rhythms and improves metabolism by prolonging the daily fast, which in turn activates cellular pathways that . . .