Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriatic arthropathy

A case of Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriasis and psoriatic arthropathy is described. This potentially fatal event was probably precipitated by an interaction between methotrexate and concurrent non-steroidal anti-inflammatory drugs, resulting in...

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Veröffentlicht in:	Annals of the rheumatic diseases 1989-03, Vol.48 (3), p.247-249
Hauptverfasser:	Wallis, P J, Ryatt, K S, Constable, T J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Arthritis - drug therapy Biological and medical sciences Drug Synergism Drug Therapy, Combination Drug toxicity and drugs side effects treatment Female Humans Ibuprofen - administration & dosage Ibuprofen - adverse effects Immunosuppression - adverse effects Medical sciences Methotrexate - administration & dosage Methotrexate - adverse effects Pharmacology. Drug treatments Pneumonia, Pneumocystis - etiology Psoriasis - drug therapy Toxicity: blood
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Beschreibung
Zusammenfassung:	A case of Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriasis and psoriatic arthropathy is described. This potentially fatal event was probably precipitated by an interaction between methotrexate and concurrent non-steroidal anti-inflammatory drugs, resulting in serious potentiation of the effects of methotrexate.
ISSN:	0003-4967 1468-2060
DOI:	10.1136/ard.48.3.247