The roles of sub‐micron and microscale roughness on shear‐driven thrombosis on titanium alloy surfaces

Background Continuous‐flow ventricular assist devices (cfVADs) are implanted in patients with end‐stage heart failure to assist with blood circulation. However, VAD implantation is associated with dangerous thrombotic complications. Our goal was to determine the impact of micron and sub‐micron scale...

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Veröffentlicht in:	Artificial organs 2023-03, Vol.47 (3), p.490-501
Hauptverfasser:	Jayaraman, Anjana, Kang, Junhyuk, Antaki, James F., Kirby, Brian J.
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Aggregates Algorithms Alloys Biomaterials Biomedical materials Blood circulation Blood clots Blood Platelets Complications Congestive heart failure embolism Fluorescence Fluorescence microscopy Humans Image processing Microfluidics Platelets Production costs Shear Surface Properties Surface roughness Surgical implants Thromboembolism Thrombosis Ti6Al4V Titanium - chemistry Titanium alloys Titanium base alloys Ventricle ventricular assist device Ventricular assist devices
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