Philadelphia positive acute lymphoblastic leukemia 16 years after the apparent cure of acute lymphoblastic leukemia. New leukemia or late relapse?

A Philadelphia-positive ALL in an adult occurring 21 years after the initial diagnosis is reported here. This case raises the question as to whether or not this event is a relapse or a new leukemia. A possible role of interferon-alpha previously administered to the patient for a chronic viral hepati...

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Veröffentlicht in:	Haematologica (Roma) 1998-09, Vol.83 (9), p.855
Hauptverfasser:	Navarro, JL, de Blas Orlando, J, Rios Herranz, E, Gonzalez Campos, J, Parody, R, Rodriguez Fernandez, JM
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - adverse effects Burkitt Lymphoma - diagnosis Diagnosis, Differential Fatal Outcome Hepatitis C - drug therapy Hepatitis, Chronic - drug therapy Humans Interferon-alpha - adverse effects Interferon-alpha - therapeutic use Male Neoplasms, Second Primary - diagnosis Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Recurrence Time Factors
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Zusammenfassung:	A Philadelphia-positive ALL in an adult occurring 21 years after the initial diagnosis is reported here. This case raises the question as to whether or not this event is a relapse or a new leukemia. A possible role of interferon-alpha previously administered to the patient for a chronic viral hepatitis is discussed too.
ISSN:	0390-6078 1592-8721