Stage IV Malignant Intrapericardial Germ Cell Tumor: A Case Report

The mediastinum is a common site for germ cell tumors. We describe an unusual case in an 18-month-old girl who presented with respiratory distress and cardiomegaly. An echocardiogram revealed a large pericardial effusion and a mass adjacent to the heart. She underwent detailed investigation and at o...

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Veröffentlicht in:Pediatric hematology and oncology 1997, Vol.14 (5), p.451-455
Hauptverfasser: Bath, L. E., Walayat, M., Mankad, P., Godman, M. J., Wallace, W. H. B.
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Sprache:eng
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Zusammenfassung:The mediastinum is a common site for germ cell tumors. We describe an unusual case in an 18-month-old girl who presented with respiratory distress and cardiomegaly. An echocardiogram revealed a large pericardial effusion and a mass adjacent to the heart. She underwent detailed investigation and at open exploration was found to have a wholly intrapericardial malignant yolk sac tumor. Staging investigations revealed a bony metastasis. The serum marker alpha-fetoprotein was elevated. She was treated with chemotherapy and is in remission 1 year after completion of treatment. We review the methods of diagnosis and follow-up of children with these tumors.
ISSN:0888-0018
1521-0669
DOI:10.3109/08880019709028775