Effects of neutralizing antibodies on cytokine treatment for anti-GBM nephritis in mouse

The process of glomerular injury in nephrotoxic serum nephritis (NTN) is dependent on proinflammatory cytokines. In the present investigation, we assessed the actions of neutralizing antibody against IL-1, 9, TNF-α, IL-6 and TGF-β1 on glomerular injury. Marked increase in IL-1 and IL-6 was detected...

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Veröffentlicht in:	Nihon Jinzo Gakkai shi 1996, Vol.38(12), pp.563-570
Hauptverfasser:	HATTORI, Tomohisa, FUJITSUKA, Naoki, KUROGI, Akiko, SHINDO, Shoichiro
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Anti-GBM nephritis, Interleukin-1β, TNF-α, Interleukin-6 Antibodies - immunology Autoantibodies Cytokines - immunology Glomerulonephritis - immunology Glomerulonephritis - pathology Interleukin-1 - immunology Interleukin-6 - immunology Kidney Glomerulus - immunology Mice Mice, Inbred BALB C Tumor Necrosis Factor-alpha - immunology
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