Bone marrow aplasia related to ticlopidine

Bone marrow aplasia related to ticlopidine

The authors report two cases of bone marrow aplasia observed 2 months after initiation of a treatment with ticlopidine. The outcome was favorable after discontinuation of therapy. The frequency of this severe drug-induced complication seems to have been underestimated. The absolute necessity of a ca...

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Veröffentlicht in:La revue de medecine interne 1996, Vol.17 (12), p.1032
Hauptverfasser: de Jaureguiberry, J P, Galzin, M, Talard, P, Marlier, S, Durupt, S, Bouchiat, C, Dussarat, G V, Jaubert, D
Format: Artikel
Sprache:fre
Schlagworte:
Aged
Bone Marrow Diseases - chemically induced
Bone Marrow Diseases - physiopathology
Hematologic Diseases - chemically induced
Humans
Male
Middle Aged
Platelet Aggregation Inhibitors - adverse effects
Ticlopidine - adverse effects
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Zusammenfassung:The authors report two cases of bone marrow aplasia observed 2 months after initiation of a treatment with ticlopidine. The outcome was favorable after discontinuation of therapy. The frequency of this severe drug-induced complication seems to have been underestimated. The absolute necessity of a careful haematological survey during the first 3 months of therapy is pointed out.
ISSN:0248-8663