Postpolio Syndrome-Response to Deprenyl (Selegiline)

Two patients with postpolio syndrome are presented. The first case developed mild Parkinson's syndrome, for which she was treated with a levodopa/carbidopa combination followed by the institution of deprenyl. An unexpected improvement in the symptoms of postpolio syndrome was noted. The second...

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Veröffentlicht in:	International journal of neuroscience 1993, Vol.71 (1-4), p.183-188
Hauptverfasser:	Bamford, Colin R, Montgomery, Erwin B, Munoz, Jorge E, Stumpf, Carol, Pry, Sherry, Namerow, Norman S
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants. Antiepileptics. Antiparkinson agents Biological and medical sciences Carbamazepine - therapeutic use deprenyl Female Humans Male Medical sciences Middle Aged Neuropharmacology Pain - physiopathology Parkinson's syndrome Pharmacology. Drug treatments Poliomyelitis Postpolio syndrome Postpoliomyelitis Syndrome - drug therapy Postpoliomyelitis Syndrome - physiopathology selegiline Selegiline - therapeutic use
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Beschreibung
Zusammenfassung:	Two patients with postpolio syndrome are presented. The first case developed mild Parkinson's syndrome, for which she was treated with a levodopa/carbidopa combination followed by the institution of deprenyl. An unexpected improvement in the symptoms of postpolio syndrome was noted. The second patient who was unaffected by Parkinson's syndrome was started on deprenyl alone and reported a similar improvement in symptomatology
ISSN:	0020-7454 1563-5279 1543-5245
DOI:	10.3109/00207459309000603