Acute colitis related to penicillin and penicillin derivatives

5 cases of acute transient colitis associated with the ingestion of ampicillin, an ampicillin derivative, and penicillin are discussed. The clinical presentation, course, and radiographic and sigmoidoscopic findings are distinct from those in pseudomembranous colitis. The colonic changes may be rela...

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Veröffentlicht in:	The Lancet (British edition) 1978-09, Vol.2 (8092 Pt 1), p.707
Hauptverfasser:	Toffler, R B, Pingoud, E G, Burrell, M I
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Amoxicillin - adverse effects Ampicillin - adverse effects Barium Sulfate Diarrhea - chemically induced Diarrhea - diagnosis Enema Enterocolitis, Pseudomembranous - chemically induced Enterocolitis, Pseudomembranous - diagnosis Female Humans Male Melena - chemically induced Melena - diagnosis Penicillins - administration & dosage Penicillins - adverse effects
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Zusammenfassung:	5 cases of acute transient colitis associated with the ingestion of ampicillin, an ampicillin derivative, and penicillin are discussed. The clinical presentation, course, and radiographic and sigmoidoscopic findings are distinct from those in pseudomembranous colitis. The colonic changes may be related to an allergic reaction in the intestine which results primarily in transient ischaemia. The presenting symptom is blood diarrhoea, and barium enema is the most productive diagnostic examination.
ISSN:	0140-6736