Positive Selection of Self- and Alloreactive CD8+T Cells in Tap-1 Mutant Mice

Mice with a homozygous deletion in their Tap-1 gene (-/- mice) express very low levels of cell membrane major histocompatibility complex class I molecules and have$

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1994-07, Vol.91 (14), p.6525-6528
Hauptverfasser:	Aldrich, Carla J., Ljunggren, Hans-Gustaf, Van Kaer, Luc, Ashton-Richardt, Philip G., Tonegawa, Susumu, Forman, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens ATP Binding Cassette Transporter, Subfamily B, Member 2 ATP-Binding Cassette Transporters beta 2-Microglobulin - genetics beta 2-Microglobulin - immunology Carrier Proteins - genetics Carrier Proteins - immunology Cell membranes Cultured cells Cytotoxicity, Immunologic H-2 Antigens - immunology Immunity (Disease) Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Mutant Strains Microbiology Molecules Neoplasm Transplantation Positive selection Proteins Rodents Spleen - immunology Spleen cells Splenocytes T lymphocytes T-Lymphocytes - immunology T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Mice with a homozygous deletion in their Tap-1 gene (-/- mice) express very low levels of cell membrane major histocompatibility complex class I molecules and have$
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.91.14.6525