Induction of Ovarian Function by Using Short-Term Human Menopausal Gonadotrophin in Patients with Ovarian Failure Following Cytotoxic Chemotherapy for Haematological Malignancy

Currently no treatment has proved successful in inducing ovarian steroidogenic and/or ga-metogenic recovery in patients with haematological malignancies treated by cytotoxic chemotherapy once biochemical failure becomes manifest i.e., when FSH levels exceed 40 IU/ L. This paper reports two such cases with classical biochemical ovarian failure in which ovarian function was induced by brief stimulation with Human Menopausal Gonadotrophin (HMG).