INTRAVASCULAR SPILL OF HYPEROSMOLAR UREA DURING INDUCED MIDTRIMESTER ABORTION

Intravascular spill of hypertonic sodium chloride and the resultant serious and occasionally fatal consequences have been reported in association with induced midtrimester abortion. This report details 3 cases of intravascular spill of hyperosmolar urea. Although urea may pose less concern, because...

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Veröffentlicht in:Obstetrics and gynecology (New York. 1953) 1979-01, Vol.53 (1), p.127-130
Hauptverfasser: Kovasznay, Beatrice M, Burkman, Ronald T, Atienza, Milagros F, King, Theodore M
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container_title Obstetrics and gynecology (New York. 1953)
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creator Kovasznay, Beatrice M
Burkman, Ronald T
Atienza, Milagros F
King, Theodore M
description Intravascular spill of hypertonic sodium chloride and the resultant serious and occasionally fatal consequences have been reported in association with induced midtrimester abortion. This report details 3 cases of intravascular spill of hyperosmolar urea. Although urea may pose less concern, because of its ability to readily cross cell membranes and its action as an osmotic diuretic, inadvertent intravascular spill can produce symptoms that include nausea, headache, sensations of warmth, and intense uterine cramping. In addition, abnormal blood pigments may occasionally be noted in the urine. Treatment includes intravenous hydration, careful monitoring of fluid/electrolyte balance and renal function, and avoiding the use of oxytocic agents.
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identifier ISSN: 0029-7844
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source MEDLINE; Journals@Ovid Complete
subjects Abortion, Induced - adverse effects
Adult
Blood Urea Nitrogen
Blood Vessels
Diuresis
Female
Headache - chemically induced
Humans
Infusions, Parenteral
Muscle Cramp - chemically induced
Osmolar Concentration
Pregnancy
Pregnancy Trimester, Second
Urea - adverse effects
Urea - therapeutic use
Uterus - drug effects
Water-Electrolyte Balance
title INTRAVASCULAR SPILL OF HYPEROSMOLAR UREA DURING INDUCED MIDTRIMESTER ABORTION
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