Familial type II hyperlipoproteinemia with coronary heart disease: effect of diet-colestipol-nicotinic acid treatment
Heterozygous familial type II hyperlipoproteinemia (F type II) is primarily manifested in hypercholesterolemia (due to low density lipoprotein-cholesterol [LDL-C] elevation) and premature coronary heart disease (CHD). We studied sequentially the effects of low cholesterol-low saturated fat-low simpl...
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Veröffentlicht in: | Chest 1981-03, Vol.79 (3), p.286 |
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Sprache: | eng |
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Zusammenfassung: | Heterozygous familial type II hyperlipoproteinemia (F type II) is primarily manifested in hypercholesterolemia (due to low
density lipoprotein-cholesterol [LDL-C] elevation) and premature coronary heart disease (CHD). We studied sequentially the
effects of low cholesterol-low saturated fat-low simple carbohydrate diet; diet and colestipol, 30 g/day; and diet, colestipol,
plus nicotinic acid (NA) 3 to 7 g/day on plasma cholesterol (Ch), LDL-C, triglyceride (TG), high density lipoprotein-cholesterol
(HDL-C) and angiographically documented coronary arterial lesions of 32 F type II patients. Effective control of F type II
resulted in arresting the progression of angiographically demonstrated coronary arterial lesions. |
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ISSN: | 0012-3692 1931-3543 |
DOI: | 10.1378/chest.79.3.286 |