Levamisole augmentation of PPD-induced lymphocyte proliferation

Levamisole augmentation of PPD-induced lymphocyte proliferation

The effect of levamisole (LMS) on PPD-induced lymphocyte proliferation in vitro has been investigated in 12 patients with pulmonary tuberculosis and 7 healthy tuberculin-positive control subjects. The augmentative effect of LMS was variable when used directly in vitro and also after pre-incubation o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:South African medical journal 1981-01, Vol.59 (4), p.109-110
1. Verfasser: Gatner, E.M.S.
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Immunology
Levamisole - pharmacology
Levamisole augmentation
Lymphocyte Activation
Lymphocyte proliferation
Lymphocytosis - chemically induced
Pharmacology
Tuberculosis
Tuberculosis, Pulmonary - blood
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The effect of levamisole (LMS) on PPD-induced lymphocyte proliferation in vitro has been investigated in 12 patients with pulmonary tuberculosis and 7 healthy tuberculin-positive control subjects. The augmentative effect of LMS was variable when used directly in vitro and also after pre-incubation of the donor cells with LMS. After ingestion of a single 150 mg dose of LMS, lymphocytes from the control subjects showed significant increased responses in PHA- and PPD-induced lymphocyte proliferation.
ISSN:0256-9574
2078-5135