Chronic biological effects of methyl methacrylate vapor: II. Body and tissue weights, blood chemistries, and gross metabolic performance in the rat
Chronic exposures of mature male Sprague-Dawley rats to near threshold-limit value (TLV) concentrations of methyl methacrylate (MMA) monomer vapor were conducted in order to assess the effects of such exposures on gross metabolic performance. There was no significant effect on food or water intake o...
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| Veröffentlicht in: | Environmental research 1980, Vol.21 (1), p.108-116 |
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| container_title | Environmental research |
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| creator | Tansy, Martin F. Hohenleitner, Frank J. Landin, Wendell E. Kendall, Frank M. |
| description | Chronic exposures of mature male Sprague-Dawley rats to near threshold-limit value (TLV) concentrations of methyl methacrylate (MMA) monomer vapor were conducted in order to assess the effects of such exposures on gross metabolic performance. There was no significant effect on food or water intake or water excretion. Average fecal excretion during the exposure portion of the week tended to be higher in the exposed than in sham-exposed rats. These differences were absent for average values obtained on weekends. Final mean body, adrenal, epididymal fat pad, and popliteal fat pad weights were not significantly different. |
| doi_str_mv | 10.1016/0013-9351(80)90013-4 |
| format | Article |
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Final mean body, adrenal, epididymal fat pad, and popliteal fat pad weights were not significantly different.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1016/0013-9351(80)90013-4</identifier><identifier>PMID: 7389692</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adrenal Glands - drug effects ; Adrenal Glands - pathology ; Animals ; Body Weight - drug effects ; Defecation ; Drinking - drug effects ; Eating - drug effects ; Liver - drug effects ; Liver - pathology ; Male ; Maximum Allowable Concentration ; Methylmethacrylates - toxicity ; Organ Size - drug effects ; Rats ; Respiration ; Time Factors</subject><ispartof>Environmental research, 1980, Vol.21 (1), p.108-116</ispartof><rights>1980</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0013-9351(80)90013-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7389692$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tansy, Martin F.</creatorcontrib><creatorcontrib>Hohenleitner, Frank J.</creatorcontrib><creatorcontrib>Landin, Wendell E.</creatorcontrib><creatorcontrib>Kendall, Frank M.</creatorcontrib><title>Chronic biological effects of methyl methacrylate vapor: II. 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Final mean body, adrenal, epididymal fat pad, and popliteal fat pad weights were not significantly different.</description><subject>Adrenal Glands - drug effects</subject><subject>Adrenal Glands - pathology</subject><subject>Animals</subject><subject>Body Weight - drug effects</subject><subject>Defecation</subject><subject>Drinking - drug effects</subject><subject>Eating - drug effects</subject><subject>Liver - drug effects</subject><subject>Liver - pathology</subject><subject>Male</subject><subject>Maximum Allowable Concentration</subject><subject>Methylmethacrylates - toxicity</subject><subject>Organ Size - drug effects</subject><subject>Rats</subject><subject>Respiration</subject><subject>Time Factors</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kd1KxDAQhYMouq6-gUIuFawmTdptvBB08WdB8EavQ5pMtpF2syTZlT6HL2y7ilfDzBnOHL5B6IySa0poeUMIZZlgBb2oyKXYdXwPTSgRZUZEwfbR5H_lCB3H-Dm0tGDkEB3OWCVKkU_Q97wJfuU0rp1v_dJp1WKwFnSK2FvcQWr6dleUDn2rEuCtWvtwixeLa_zgTY_VyuDkYtwA_gK3bFK8wnXrvcG6gc7FFBwMo3FtGXyMo5uqfTscXUOwPnRqpQG7FU4N4KDSCTqwqo1w-len6OPp8X3-kr2-PS_m968Z5JynrBQzwbUqK8s08LIEqDRYU_OCMlLkTClaWF6Lmc6Z4CqvZpwanVtac8OZMWyKzn9915u6AyPXwXUq9PIPzqDf_eowhNg6CDJqB0NW48IASBrvJCVyfIYcScuRtKyI3D1DcvYDaAR9eQ</recordid><startdate>1980</startdate><enddate>1980</enddate><creator>Tansy, Martin F.</creator><creator>Hohenleitner, Frank J.</creator><creator>Landin, Wendell E.</creator><creator>Kendall, Frank M.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>1980</creationdate><title>Chronic biological effects of methyl methacrylate vapor: II. 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Body and tissue weights, blood chemistries, and gross metabolic performance in the rat</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>1980</date><risdate>1980</risdate><volume>21</volume><issue>1</issue><spage>108</spage><epage>116</epage><pages>108-116</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><abstract>Chronic exposures of mature male Sprague-Dawley rats to near threshold-limit value (TLV) concentrations of methyl methacrylate (MMA) monomer vapor were conducted in order to assess the effects of such exposures on gross metabolic performance. There was no significant effect on food or water intake or water excretion. Average fecal excretion during the exposure portion of the week tended to be higher in the exposed than in sham-exposed rats. These differences were absent for average values obtained on weekends. Final mean body, adrenal, epididymal fat pad, and popliteal fat pad weights were not significantly different.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>7389692</pmid><doi>10.1016/0013-9351(80)90013-4</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0013-9351 |
| ispartof | Environmental research, 1980, Vol.21 (1), p.108-116 |
| issn | 0013-9351 1096-0953 |
| language | eng |
| recordid | cdi_pubmed_primary_7389692 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adrenal Glands - drug effects Adrenal Glands - pathology Animals Body Weight - drug effects Defecation Drinking - drug effects Eating - drug effects Liver - drug effects Liver - pathology Male Maximum Allowable Concentration Methylmethacrylates - toxicity Organ Size - drug effects Rats Respiration Time Factors |
| title | Chronic biological effects of methyl methacrylate vapor: II. Body and tissue weights, blood chemistries, and gross metabolic performance in the rat |
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