Chronic biological effects of methyl methacrylate vapor: II. Body and tissue weights, blood chemistries, and gross metabolic performance in the rat

Chronic exposures of mature male Sprague-Dawley rats to near threshold-limit value (TLV) concentrations of methyl methacrylate (MMA) monomer vapor were conducted in order to assess the effects of such exposures on gross metabolic performance. There was no significant effect on food or water intake o...

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Veröffentlicht in:Environmental research 1980, Vol.21 (1), p.108-116
Hauptverfasser: Tansy, Martin F., Hohenleitner, Frank J., Landin, Wendell E., Kendall, Frank M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Chronic exposures of mature male Sprague-Dawley rats to near threshold-limit value (TLV) concentrations of methyl methacrylate (MMA) monomer vapor were conducted in order to assess the effects of such exposures on gross metabolic performance. There was no significant effect on food or water intake or water excretion. Average fecal excretion during the exposure portion of the week tended to be higher in the exposed than in sham-exposed rats. These differences were absent for average values obtained on weekends. Final mean body, adrenal, epididymal fat pad, and popliteal fat pad weights were not significantly different.
ISSN:0013-9351
1096-0953
DOI:10.1016/0013-9351(80)90013-4