Lorazepam-related withdrawal seizures

Lorazepam is a new member of a constantly growing benzodiazepine family. It has been demonstrated to be an effective anxiolytic agent, but as with use of other drugs of this nature, tolerance and dependence may occur. These unwanted effects can constitute a serious clinical problem. We report on two...

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Veröffentlicht in:	Mayo Clinic proceedings 1980-03, Vol.55 (3), p.190
Hauptverfasser:	de la Fuente, J R, Rosenbaum, A H, Martin, H R, Niven, R G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Anxiety Agents Epilepsy, Tonic-Clonic - etiology Female Humans Lorazepam - blood Pregnancy Pregnancy Complications - etiology Substance Withdrawal Syndrome - etiology Time Factors
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Zusammenfassung:	Lorazepam is a new member of a constantly growing benzodiazepine family. It has been demonstrated to be an effective anxiolytic agent, but as with use of other drugs of this nature, tolerance and dependence may occur. These unwanted effects can constitute a serious clinical problem. We report on two patients with grand mal seizures, which were thought to be secondary to abrupt withdrawal of lorazepam. Because these types of agents are the most widely used drugs in medical practice, their potential risks must be emphasized.
ISSN:	0025-6196