Effect of Whole Body Irradiation on Colony Production by Bone Marrow Cells in vitro

Summary With increasing doses of whole body irradiation there was an exponential decrease in the percentage of cells in the bone marrow capable of in vitro colony formation. This decrease was correlated with a fall in the percentage of small lymphocytes in the bone marrow suggesting that the in vitr...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1967-06, Vol.125 (2), p.388-391
Hauptverfasser:	Robinson, W. A., Bradley, T. R., Metcalf, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	ANIMAL CELLS Animals BONE MARROW Bone Marrow - radiation effects Bone Marrow Cells BONE MARROW/radiation effects on in vitro growth of cells of, of mice, whole-body x CELLS/radiation effects on in vitro growth of bone marrow, of mice, whole body x Culture Techniques DETERMINATION ENVIRONMENT EXPANSION IRRADIATION LYMPHOCYTES LYMPHOCYTES/radiation effects on in vitro colony forming ability of, in bone marrow of mice, whole-body x Male MEDICINE MICE MICE/ radiation effects on in vitro growth of bone marrow cells of, whole-body x N28620 -Life Sciences-Radiation Effects on Animals- Vertebrates RADIATION DOSES RADIATION EFFECTS REPRODUCTION TESTING TIME USES X RADIATION X RADIATION/effects on in vitro colony forming ability of bone marrow cells of mice whole-body
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Zusammenfassung:	Summary With increasing doses of whole body irradiation there was an exponential decrease in the percentage of cells in the bone marrow capable of in vitro colony formation. This decrease was correlated with a fall in the percentage of small lymphocytes in the bone marrow suggesting that the in vitro colony forming cells are members of the small lymphocyte population.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-125-32099