Effect of 5-Bromodeoxyuridine on the Hemolysin Response in Rabbits.

Summary The analogue, 5-bromodeoxyuri-dine, when injected intraperitoneally within an hour and a half of an intravenous injection of sheep red blood cells, produced an unequivocal adjuvant effect on the hemolysin response in unirradiated rabbits as gauged by high peak titer. It was, however, ineffec...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1967-02, Vol.124 (2), p.671-675
Hauptverfasser:	Taliaferro, William H., Taliaferro, Lucy Graves
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Formation - radiation effects Antigens Bromodeoxyuridine - pharmacology Erythrocytes Hemolysin Proteins - metabolism Rabbits Radiation Effects
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Beschreibung
Zusammenfassung:	Summary The analogue, 5-bromodeoxyuri-dine, when injected intraperitoneally within an hour and a half of an intravenous injection of sheep red blood cells, produced an unequivocal adjuvant effect on the hemolysin response in unirradiated rabbits as gauged by high peak titer. It was, however, ineffective when injected 2 days after the sheep red cells into unirradiated rabbits and did not modify X-ray-induced enhancement or depression when it and the antigen were injected one day before and one day after 400 R, respectively.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-124-31821