Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats
Summary Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1969-03, Vol.130 (3), p.860-863 |
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| container_end_page | 863 |
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| container_issue | 3 |
| container_start_page | 860 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 130 |
| creator | Goyer, R. A. Reynolds, J. O. Elston, R. C. |
| description | Summary
Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids. |
| doi_str_mv | 10.3181/00379727-130-33673 |
| format | Article |
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Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-130-33673</identifier><identifier>PMID: 5773680</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Amino Acids - metabolism ; Animals ; Chromatography, Ion Exchange ; Cyclopentanes - pharmacology ; Cystinuria ; Injections, Intraperitoneal ; Kidney Tubules - metabolism ; Male ; Rats ; Renal Aminoacidurias - chemically induced</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1969-03, Vol.130 (3), p.860-863</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-e68cd0e74e6bf0a09a468cec82effb442dedb69c81ce281c6714ebbfa23811e63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5773680$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goyer, R. A.</creatorcontrib><creatorcontrib>Reynolds, J. O.</creatorcontrib><creatorcontrib>Elston, R. C.</creatorcontrib><title>Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.</description><subject>Amino Acids - metabolism</subject><subject>Animals</subject><subject>Chromatography, Ion Exchange</subject><subject>Cyclopentanes - pharmacology</subject><subject>Cystinuria</subject><subject>Injections, Intraperitoneal</subject><subject>Kidney Tubules - metabolism</subject><subject>Male</subject><subject>Rats</subject><subject>Renal Aminoacidurias - chemically induced</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN1KwzAUx4Moc05fQBDyAnFJ0ybt5ShOhYEy9Lqm6cmW0Y-RpBd7ezM3vfTmHDj_Dzg_hO4ZfeQsZ3NKuSxkIgnjlHAuJL9AU5bxjHBRFJdoejSQo-Ma3Xi_o5RlMhETNMmk5CKnU_RVbpVTOoCzPljt8WBw2AJedLYflLbN6KzCa_BjG2y_wcYNHS4Puh1aGLXto7OJ1hh2Ktihx7bH78o6soQGr1Xwt-jKqNbD3XnP0Ofy6aN8Iau359dysSKa8zwQELluKMgURG2oooVK4wV0noAxdZomDTS1KHTONCRxCMlSqGujEp4zBoLPUHLq1W7w3oGp9s52yh0qRqsjreqXVhVpVT-0YujhFNqPdQfNX-SMJ-rzk-7VBqrdMLo-_vBf4zfo9XTs</recordid><startdate>196903</startdate><enddate>196903</enddate><creator>Goyer, R. A.</creator><creator>Reynolds, J. O.</creator><creator>Elston, R. C.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>196903</creationdate><title>Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats</title><author>Goyer, R. A. ; Reynolds, J. O. ; Elston, R. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-e68cd0e74e6bf0a09a468cec82effb442dedb69c81ce281c6714ebbfa23811e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1969</creationdate><topic>Amino Acids - metabolism</topic><topic>Animals</topic><topic>Chromatography, Ion Exchange</topic><topic>Cyclopentanes - pharmacology</topic><topic>Cystinuria</topic><topic>Injections, Intraperitoneal</topic><topic>Kidney Tubules - metabolism</topic><topic>Male</topic><topic>Rats</topic><topic>Renal Aminoacidurias - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goyer, R. A.</creatorcontrib><creatorcontrib>Reynolds, J. O.</creatorcontrib><creatorcontrib>Elston, R. C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goyer, R. A.</au><au>Reynolds, J. O.</au><au>Elston, R. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1969-03</date><risdate>1969</risdate><volume>130</volume><issue>3</issue><spage>860</spage><epage>863</epage><pages>860-863</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>5773680</pmid><doi>10.3181/00379727-130-33673</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1969-03, Vol.130 (3), p.860-863 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_pubmed_primary_5773680 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Amino Acids - metabolism Animals Chromatography, Ion Exchange Cyclopentanes - pharmacology Cystinuria Injections, Intraperitoneal Kidney Tubules - metabolism Male Rats Renal Aminoacidurias - chemically induced |
| title | Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats |
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