Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats

Characteristics of the Aminoaciduria Resulting from Cycloleucine Administration in Pair-Fed Rats

Summary Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1969-03, Vol.130 (3), p.860-863
Hauptverfasser: Goyer, R. A., Reynolds, J. O., Elston, R. C.
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acids - metabolism
Animals
Chromatography, Ion Exchange
Cyclopentanes - pharmacology
Cystinuria
Injections, Intraperitoneal
Kidney Tubules - metabolism
Male
Rats
Renal Aminoacidurias - chemically induced
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Zusammenfassung:Summary Cycloleucine administration to rats produces a generalized aminoaciduria which is largely the result of failure of renal tubular reabsorption. The greatest competition for renal tubular transport appears to be with the site for the dibasic amino acids.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-130-33673