Hepatic Triglyceride and Lipoprotein Lipase Activities of Post-heparin Plasma in Normals and Hypertriglyceridemics

Post-heparin plasma hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL) activities were 8-34 and 3.5-21 (range) μmol ml hr respectively in males with normal serum lipid concentrations. In females the corresponding values were 4-25 and 4-16 μmol ml hr. No significant differences were observed between ages or between the two sexes. Male patients with hypertriglyceridaemia had similar activities of H-TGL but significantly lower values for LPL activities than the control males. Significant linear correlations were found between serum triglyceride concentrations and LPL activities both for males (coefficient of correlation = r = −0.64) and for females (r = −0.62).