Cushingʼs Syndrome Complicating Pregnancy: A Case Report

A 29-year-old patient developed severe Cushingʼs syndrome shortly after becoming pregnant. The syndrome was characterized by hypokalemia and a marked rise in urinary 17-hydroxycorticosteroids, which could not be suppressed with dexamethasone, 8 mg daily. Clinical and biochemical abnormalities disapp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 1971-12, Vol.38 (6), p.841-843
Hauptverfasser:	WIELAND, RALPH G, SHAFFER, MARK B, GLOVE, RICHARD P
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxycorticosteroids - blood 17-Hydroxycorticosteroids - urine 17-Ketosteroids - urine Abortion, Therapeutic Adrenal Gland Neoplasms - complications Adult Chorionic Gonadotropin - pharmacology Cushing Syndrome - chemically induced Cushing Syndrome - complications Cushing Syndrome - drug therapy Cushing Syndrome - therapy Dexamethasone - administration & dosage Estrogens - pharmacology Female Humans Hypokalemia - complications Potassium - therapeutic use Pregnancy Pregnancy Complications
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A 29-year-old patient developed severe Cushingʼs syndrome shortly after becoming pregnant. The syndrome was characterized by hypokalemia and a marked rise in urinary 17-hydroxycorticosteroids, which could not be suppressed with dexamethasone, 8 mg daily. Clinical and biochemical abnormalities disappeared rapidly after an abortion. Efforts to reproduce the abnormalities afterward with human chorionic gonadotropin and a synthetic estrogen were unsuccessful. This represents the only reported example in which a therapeutic abortion resulted in the remission of Cushingʼs syndrome.
ISSN:	0029-7844 1873-233X