Alterations in DMBA-Induced Rat Mammary Tumors by Actinomycin D
Actinomycin D not only protected against the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene, but also influenced the nature of those tumors that developed. Fewer glandular neoplasms, and more secretory adenomas and fibroadenomas were formed. Histologic distinctions among the vario...
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| Veröffentlicht in: | JNCI : Journal of the National Cancer Institute 1973-04, Vol.50 (4), p.915-920 |
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| container_title | JNCI : Journal of the National Cancer Institute |
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| creator | Gardner, H. Allen Kellen, J. A. Anderson, K. M. |
| description | Actinomycin D not only protected against the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene, but also influenced the nature of those tumors that developed. Fewer glandular neoplasms, and more secretory adenomas and fibroadenomas were formed. Histologic distinctions among the various mammary nodules are described, and it is stressed that evaluation of experimental data without consideration of the histologic nature of the nodules may be invalid. |
| doi_str_mv | 10.1093/jnci/50.4.915 |
| format | Article |
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Histologic distinctions among the various mammary nodules are described, and it is stressed that evaluation of experimental data without consideration of the histologic nature of the nodules may be invalid.</description><subject>Adenofibroma - chemically induced</subject><subject>Adenofibroma - pathology</subject><subject>Adenoma - chemically induced</subject><subject>Adenoma - pathology</subject><subject>Animals</subject><subject>Benz(a)Anthracenes</subject><subject>Dactinomycin - therapeutic use</subject><subject>Female</subject><subject>Fibroma - chemically induced</subject><subject>Fibroma - pathology</subject><subject>Mammary Neoplasms, Experimental - chemically induced</subject><subject>Mammary Neoplasms, Experimental - pathology</subject><subject>Mammary Neoplasms, Experimental - prevention & control</subject><subject>Rats</subject><issn>0027-8874</issn><issn>1460-2105</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j0trAjEcxENpsdb22GMhXyBrssnfbE5lax8qSh9YKr0seUKsu8ruCvXbV1E6lzn8hmEGoVtGE0YV7y8rG_tAE5EoBmeoy8SAkpRROEddSlNJskyKS3TVNEu6l0pFB3WEpFxK2UX3-ar1tW7jumpwrPDj7CEn48ptrXf4Q7d4pstS1zs835brusFmh3Pbxmpd7uwhfo0ugl41_ubkPfT5_DQfjsj09WU8zKckpkK0xAgKWXBccVDcWuVNpj0EywfSS-O0tRocUxkEo3xmIQ3O2UC55QAmAOM9dHfs3WxN6V2xqeNhVnE6sufkyGPT-t9_rOufYiC5hGK0-C4mk_fZ_Eu-FQv-B2xcWeA</recordid><startdate>197304</startdate><enddate>197304</enddate><creator>Gardner, H. 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Histologic distinctions among the various mammary nodules are described, and it is stressed that evaluation of experimental data without consideration of the histologic nature of the nodules may be invalid.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>4703777</pmid><doi>10.1093/jnci/50.4.915</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0027-8874 |
| ispartof | JNCI : Journal of the National Cancer Institute, 1973-04, Vol.50 (4), p.915-920 |
| issn | 0027-8874 1460-2105 |
| language | eng |
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| source | Oxford University Press Journals Digital Archive legacy; MEDLINE |
| subjects | Adenofibroma - chemically induced Adenofibroma - pathology Adenoma - chemically induced Adenoma - pathology Animals Benz(a)Anthracenes Dactinomycin - therapeutic use Female Fibroma - chemically induced Fibroma - pathology Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - pathology Mammary Neoplasms, Experimental - prevention & control Rats |
| title | Alterations in DMBA-Induced Rat Mammary Tumors by Actinomycin D |
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