UNUSUAL PROLIFERATION OF BILE-DUCT CELLS IN ICR FEMALE MICE GIVEN 2, 7-FLUORENYLBISACETAMIDE WHILE NURSING SUCKLINGS

UNUSUAL PROLIFERATION OF BILE-DUCT CELLS IN ICR FEMALE MICE GIVEN 2, 7-FLUORENYLBISACETAMIDE WHILE NURSING SUCKLINGS

ICR female mice given diet supplemented with 0.025% 2, 7-fluorenylbisacetamide while nursing sucklings showed a unique susceptibility which led to unusual proliferation of mature and immature bile-duct cells.

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Bibliographische Detailangaben
Veröffentlicht in:GANN Japanese Journal of Cancer Research 1972/08/31, Vol.63(4), pp.507-508
Hauptverfasser: KIMURA, Ikuo, SAKUMA, Fumie, ITO, Yohei, NTSHIO, Osamu, YASUKAWA, Shiro
Format: Artikel
Sprache:eng
Schlagworte:
Acetamides - pharmacology
Aging
Animals
Bile Ducts - drug effects
Bile Ducts - pathology
Body Weight
Female
Fluorenes - pharmacology
Lactation
Liver - pathology
Male
Mice
Mice, Inbred ICR
Neoplasms, Experimental - chemically induced
Pregnancy
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Beschreibung
Zusammenfassung:ICR female mice given diet supplemented with 0.025% 2, 7-fluorenylbisacetamide while nursing sucklings showed a unique susceptibility which led to unusual proliferation of mature and immature bile-duct cells.
ISSN:0016-450X
DOI:10.20772/cancersci1959.63.4_507