Sampling Variances in Twin and Sibling Studies of Man

Sampling Variances in Twin and Sibling Studies of Man

The sampling variances in twin and sibling studies of man for estimation of intraclass correlation coefficients and their relation to heritabilities are evaluated. For twins and full-sibs the higher the estimated heritability of a trait the smaller the sampling variance. With increase in the number...

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Veröffentlicht in:Human heredity 1974-01, Vol.24 (4), p.363-372
Hauptverfasser: Kang, Ke Won, Lindemann, Jon P., Christian, Joe C., Nance, Walter E., Norton, James A.
Format: Artikel
Sprache:eng
Schlagworte:
Consanguinity
Crosses, Genetic
Female
Genetic Variation
Genetics
Humans
Phenotype
Pregnancy
Twins
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Zusammenfassung:The sampling variances in twin and sibling studies of man for estimation of intraclass correlation coefficients and their relation to heritabilities are evaluated. For twins and full-sibs the higher the estimated heritability of a trait the smaller the sampling variance. With increase in the number of twin sets or of full-sibships studied, the sampling variances decrease by their proportions. Twin and full-sib studies with lower heritabilities (h²
ISSN:0001-5652
1423-0062
DOI:10.1159/000152672