Effect of a repeated dose of terbutaline by inhalation

Effect of a repeated dose of terbutaline by inhalation

Summary The effect of repeated doses of 0.25 mg. terbutaline by inhalation given at intervals of 15 to 20 minutes on FEV1 and airways resistance have been observed in 15 patients with labile airways obstruction. It was found that an increase in FEV1 occurred after the first and second doses but not...

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Veröffentlicht in:Current medical research and opinion 1974, Vol.2 (5), p.275-280
Hauptverfasser: Chaieb, J. A., Kamburoff, P. L., Prime, F. J.
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Intranasal
Adult
Aerosols
Airway Obstruction - complications
Airway Resistance - drug effects
Asthma - complications
Blood Pressure - drug effects
Body Height
Body Weight
Bronchitis - complications
Bronchodilator agents
Dose-Response Relationship, Drug
Female
Heart Rate - drug effects
Humans
Male
Middle Aged
Pulse - drug effects
Respiration - drug effects
Respiratory Function Tests
Respiratory Therapy
terbutaline
Terbutaline - administration & dosage
Terbutaline - pharmacology
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Zusammenfassung:Summary The effect of repeated doses of 0.25 mg. terbutaline by inhalation given at intervals of 15 to 20 minutes on FEV1 and airways resistance have been observed in 15 patients with labile airways obstruction. It was found that an increase in FEV1 occurred after the first and second doses but not after the third and fourth. Airways resistance fell over the same period but continued to fall slightly thereafter up to the fifth dose. Cardiovascular effects were minimal.
ISSN:0300-7995
1473-4877
DOI:10.1185/03007997409115234